- Date: 01/29-01/30/10
- Location: Penn State-Ashenfelter Track (Banked) - University Park, PA
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- ICON KEY:
Women's 4 x 400 Relay
- Finals: Heat #1
| Place | Overall | Team | Squad | Athletes | Time | Score |
| 1. | 1 | Penn State | A | Caitlin DeFusco, Doris Anyanwu, Shavon Greaves, Fawn Dorr | 3:37.57 | - | |
| 2. | 2 | Miami | A | Jennifer Estime, Ti'erra Brown, Takecia Jameson, Tameka Jameson | 3:40.50 | - | |
| 3. | 3 | Georgetown | A | London Finley, Deidra Sanders, Tenille Stoudenmire, Abigail Johnson | 3:44.84 | - | |
| 4. | 4 | Virginia Tech | A | Yvonne Amegashie, Funmi Alabi, Ogechi Nwaneri, Aunye Boone | 3:45.51 | - | |
| 5. | 5 | Tennessee | A | Ellen Wortham, Phoebe Wright, Chanelle Price, Nyoshua Bryant | 3:45.74 | - |