- Date: 2/4 - 02/05/11
- Location: Notre Dame-Loftus Center - Notre Dame, IN
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- ICON KEY:
4 x 400 Relay
Heat 1
4 x 400 Relay
Heat 2
4 x 400 Relay
Heat 3
4 x 400 Relay
Heat 4
| Heat Pl. | Overall | Team | Squad | Athletes | Time | Score |
| 1. | 7 | Illinois State | A | Alex Roark, Fabian Norgrove, Coty Kramer, Matthew Smoody | 3:17.54 | - | |
| 2. | 13 | Windsor ON | A | Dustin Eldridge, Mitch Tome, Ben Lane, Andrew Aguanno | 3:21.44 | - | |
| 3. | 15 | Illinois-Chicago | A | Ryan Blackmon, Josh Stanner, Lewis Brown, Erik Perez | 3:24.72 | - |
| Heat Pl. | Overall | Team | Squad | Athletes | Time | Score |
| 1. | 9 | Indiana State | A | Justin Baxtron, Corey Hahn, Keenan Johnson, Ray Skamay | 3:18.76 | - | |
| 2. | 11 | Indiana | A | Joshua Moore, Joseph Holahan, Daniel Stockberger, Ryan Hindes | 3:20.15 | - | |
| 3. | 12 | Western Ontario | A | Elias Granillio, Daniel Goddard, Scott Leitch, Brent Bates | 3:21.40 | - | |
| 4. | 14 | McMaster | A | Jimmy Tat, Matt Pawelke, Scott Hutchinson, Rudy Baronette | 3:21.93 | - |
| Heat Pl. | Overall | Team | Squad | Athletes | Time | Score |
| 1. | 4 | Eastern Illinois | A | Cody Boarman, Darren Patterson, Preston Smith, Patrick Tortorici | 3:14.20 | - | |
| 2. | 5 | Notre Dame | A | Edward Hitchler, Jarrod Buchanon, Brendan Dougherty, Patrick Feeney | 3:15.24 | - | |
| 3. | 6 | Eastern Michigan | A | Chris Scott, Kyle Gill, Jairus Saunders, Brycen Spratling | 3:15.71 | - | |
| 4. | 8 | Purdue | A | Josh Lee, Jacob Palmer, Julian Merkison, Mike Willey | 3:17.92 | - | |
| 5. | 10 | Central Michigan | A | Clay Holman, Ross Parsons, Brandon Post, Christopher Thomas | 3:19.76 | - |
| Heat Pl. | Overall | Team | Squad | Athletes | Time | Score |
| 1. | 1 | Mississippi | A | Dante' Oliver, Christopher Bush, Matt Daniels, Lee Moore | 3:10.79 | - | |
| 2. | 2 | Illinois | A | Shane Daniel, Cody Wisslead, Malcolm Taylor, Daniel Jones | 3:11.94 | - | |
| 3. | 3 | Michigan | A | Matthew Campbell, David St. Amant, Eric Oliver, Carl Buchanon | 3:12.15 | - |