- Date: 4/1 - 04/02/11
- Location: SE Missouri - Cape Gigardeau, MO
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- ICON KEY:
| Place | Team | Squad | Athletes | Time | Score |
| 1. | SE Missouri | A | Angelica Larrier, Rachel Kahle, Magan Edwards, Jerika Lewis | 46.42 | - | |
| 2. | Arkansas State | A | Jamie Curry, Charmisha Morrow, Verlisa Pryor, Sharika Nelvis | 46.45 | - | |
| 3. | SE Missouri | B | Unique Hooks, Triona Roberts, Travon Beard, Mary Pearson | 50.03 | - |