- Date: 04/16/11
- Location: Ohio Wesleyan - Delaware, OH
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- ICON KEY:
4 x 400 Relay
Heat 1
4 x 400 Relay
Heat 2
| Heat Pl. | Overall | Team | Squad | Athletes | Time | Score |
| 1. | 1 | Mount Union | A | Emily Mazzaferri, Heather Potts, Alexis Campbell, Mary Mahoney | 4:02.24 | 10 | |
| 2. | 2 | Oberlin | A | Sybil Levine, Amanda Miller, Melissa Elie, Marissa Clardy | 4:04.77 | 8 | |
| 3. | 3 | Otterbein | A | Samie Corbin, Sam Stolarz, Lindsay Main, Jocelyn Hennon | 4:08.12 | 6 | |
| 4. | 4 | Capital | A | Caitlin Prange, Emma McCarron, Kwesi Seabrook, Sarah Trick | 4:09.34 | 5 | |
| 5. | 5 | Kenyon | A | Beth Dahlburg, Cary Watts, Alexia Derkasch, Kirkley Doyle | 4:10.31 | 4 | |
| 6. | 7 | Ohio Wesleyan | A | Katelyn Nance, Lindsay Dunbar, Emily Satler, Lainey Kekic | 4:11.69 | 2 | |
| 7. | 8 | Baldwin-Wallace | A | Nicole Smith, Brittany Sterling, Jamie Clapacs, Kimberly Chinn | 4:12.78 | 1 |
| Heat Pl. | Overall | Team | Squad | Athletes | Time | Score |
| 1. | 6 | John Carroll | A | Maureen Creighton, Nicki Bohrer, Gab Kreuz, Maribeth Keppler | 4:10.35 | 3 | |
| 2. | 9 | Wooster | A | Kelsie Herring, Taylor Morgan, Jean Quenneville, Whitney Rappole | 4:15.83 | - | |
| 3. | 10 | Heidelberg | A | Lillian Hansberger, Jocelyn Staugler, Alexis Goodman, Jazmine Shaw | 4:16.11 | - | |
| 4. | 11 | Wittenberg | A | Darcy Dubuc, Samantha Iden, Shawna Johnson, Catherine Kuerbitz | 4:18.39 | - | |
| 5. | 12 | Defiance | A | Katie Heitkamp, Kali George, Erika DeBos, Courtney Swabb | 4:21.55 | - |