- Date: 2/24 - 02/25/12
- Location: Nebraska-Devaney Center - Lincoln, NE
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- ICON KEY:
- IC4A/ECAC
4 x 400 Relay
Heat 1
4 x 400 Relay
Heat 2
| Heat Pl. | Overall | Team | Squad | Athletes | Time | Score |
| 1. | 7 | Minnesota | A | Nyoka Giles, Chidera Obasih, Jessica Waldvogel, Megan Geyen | 3:44.08 | 2 | |
| 2. | 8 | Indiana | A | Ruth Christopher, Aireonna Bailey, Jordan Gray, Antonia Franklin | 3:44.36 | 1 | |
| 3. | 9 | Michigan | A | Amber Smith, Jillian Smith, Alex Williams, Brittani Williams | 3:45.14 | - | |
| 4. | 10 | Purdue | A | Morgan Monroe, Elise Glass, Ebony Woodard, Taylor Morrison | 3:45.42 | - | |
| 5. | 11 | Wisconsin | A | Katie Duchow, Carrie Edmunds, Brittney Harper, Jessica Flax | 3:45.46 | - |
| Heat Pl. | Overall | Team | Squad | Athletes | Time | Score |
| 1. | 1 | Illinois | A | Asia Thomas, Ashley Kelly, Latoya Griffith, Ashley Spencer | 3:34.89 | 10 | |
| 2. | 2 | Penn State | A | Dynasty McGee, Mahagony Jones, Kirsten Nieuwendam, Ijeoma Iheoma | 3:35.80 | 8 |
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| 3. | 3 | Michigan State | A | Brittany Lewis, Jaelynn Pryor, Alicia Evans, Alysson Bodenbach | 3:39.90 | 6 | |
| 4. | 4 | Ohio State | A | Kachay Hullum, Shaniqua McGinnis, Jacqueline Dim, Nyjah Cousar | 3:40.67 | 5 | |
| 5. | 5 | Nebraska | A | Mila Andric, Mara Weekes, Brooke Dinsdale, Ellie Grooters | 3:40.72 | 4 | |
| 6. | 6 | Iowa | A | Hannah Simonson, Ashley Liverpool, Nicole Erickson, Victoria Sack | 3:41.78 | 3 |