- Date: 03/03/12
- Location: Iowa State-Leid Rec Center - Ames, IA
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- ICON KEY:
4 x 400 Relay
Heat 1
4 x 400 Relay
Heat 2
| Heat Pl. | Overall | Team | Squad | Athletes | Time | Score |
| 1. | 1 | Texas Tech | A | Taylor Evans, Candace Jackson, Erica Alexander, Olivia Lewis | 3:34.51 | - | |
| 2. | 2 | Western Michigan | A | Andrea Arnold, Victoria Chatman, Lindsey Hufnagel, Iris Campbell | 3:36.73 | - | |
| 3. | 3 | South Carolina | A | Erika Rucker, Nadonnia Rodrigues, Christal Green, Amber Allen | 3:36.87 | - | |
| 4. | 4 | North Dakota St. | A | Brittany Page, Antoinette Goodman, Brittany Schanandore, Paige Stratioti | 3:41.12 | - |
| Heat Pl. | Overall | Team | Squad | Athletes | Time | Score |
| 1. | 5 | UMKC | A | Sakia Taylor, viola Kleiser, Briana Carter, Veronica Rollins | 3:50.39 | - | |
| 2. | 6 | North Dakota St. | B | Melissa Kitching, Ashlynn Simon, Faith Kruchowski, Deborah John | 3:50.96 | - | |
| 3. | 7 | Sioux Falls | A | Conner Anderson, Leah Wensmann, Shelbie Pettie, Mel Kroupa | 3:58.33 | - | |
| 4. | 8 | Grinnell | A | Christine Ajinjeru, Eloise Miller, Sarah Burnell, Isabelle Miller | 4:03.72 | - |