- Date: 03/24/12
- Location: Eastern Illinois - Charleston, IL
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- ICON KEY:
| Place | Team | Squad | Athletes | Time | Score |
| 1. | Eastern Illinois | A | Janessa Clay, Ashley Brown, Bridget Sanchez, Emily Quinones | 4:01.47 | - | |
| 2. | Indiana State | A | Stacia Weatherford, Brittany Housel, Carmelia Stewart, Ja'Liza Prophet | 4:03.84 | - | |
| 3. | Indiana State | B | Macey Black, Leeann Michl, Patricia Merrion, Sarah Snapp | 4:03.93 | - | |
| 4. | Indiana State | C | Shelby Higginbottom, Kaci Smith, Tori Stone, Amy Fanella | 4:04.21 | - | |
| 5. | Eastern Illinois | B | Jaida Moore, Charmaine Arnold, Paige Biehler, Erika Foltys | 4:16.07 | - |