- Date: 03/30/12
- Location: Trinity U. - San Antonio, TX
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- ICON KEY:
4 x 100 Relay
Heat 1
4 x 100 Relay
Heat 2
| Heat Pl. | Overall | Team | Squad | Athletes | Time | Score |
| 1. | 1 | UTSA | A | Shahira Ehiemua, Chiugo Okonkwo, Krystal Wynn, Jhorden Hunter | 45.63 | - | |
| 2. | 2 | TxPerformance | A | Toccata Murphy, Chauntae Bayne, Jasmin Sanford, Donna Lawrence | 46.87 | - | |
| 3. | 3 | Texas Lutheran | A | Sahara Bragner, Shyra Walker, Devin Evans, Monique Anderson | 47.32 | - | |
| 4. | 4 | Incarnate Word | A | Brittney Holcombe, Lauren Pratt, Stephanie Nelson, Shaneve Swift | 47.47 | - | |
| 5. | 5 | McMurry | A | Carla Burton, Kendra Coleman, Tiana Alexander, Shanita Coleman | 47.53 | - | |
| 6. | 6 | Hardin-Simmons | A | Halee Edwards, Aaron Livingston, Nicole Campbell, Jayci Shelton | 50.02 | - |
| Heat Pl. | Overall | Team | Squad | Athletes | Time | Score |
| 1. | 7 | Texas Wesleyan | A | Raven Alexander, J'Lesa Hutchinson, Germesha Shelton, Asia Wilson | 50.13 | - | |
| 2. | 8 | Concordia (Tex.) | A | Brianna Cunningham, Raven Alexander, Desiree De Leon, Randi Askew | 50.20 | - | |
| 3. | 9 | Trinity (Tex.) | A | Mary Kate Stewart, Salome Wilfred, Corey Callahan, Sara Breshears | 50.46 | - |