- Date: 04/14/12
- Location: Benedictine University - Lisle, IL
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- ICON KEY:
4 x 400 Relay
Heat 1
4 x 400 Relay
Heat 2
4 x 400 Relay
Heat 3
| Heat Pl. | Overall | Team | Squad | Athletes | Time | Score |
| 1. | 14 | Aurora | A | Bri Carter, Ashley Mayer, Ariana Espino, Rocky Bentsen | 4:36.40 | - | |
| 2. | 16 | Illinois Track Club | A | Kaleigh Evans, Erin Murphy, Emma Grimes, Thea Cudnowski | 4:41.00 | - | |
| 3. | 17 | Concordia (Wis.) | B | Erika Wenson, Brittany Maynard, Samantha Nelson, Sarah Maynard | 4:50.62 | - | |
| 4. | 18 | Aurora | B | Kaylee Swearingen, Kimberly Stickley, Arlette Millan, Hannah Auch | 4:51.68 | - |
| Heat Pl. | Overall | Team | Squad | Athletes | Time | Score |
| 1. | 5 | College of DuPage | A | Becca Hoder, Katie Barbour, Shenelle Burnett, Anna Deufel | 4:14.36 | 4 | |
| 2. | 6 | Olivet Nazarene | B | Tara Gonzalez, Christy Trank, Kylie Lippencott, Hannah Endrizzi | 4:15.43 | 3 | |
| 3. | 8 | Illinois Track Club | B | Monica O'Connor, Kelly Kramsey, Jessica Mulcrone, Michelle Turner | 4:17.77 | 1 | |
| 4. | 10 | Elmhurst | A | Alex Reid, Allie Epping, Jessica Cochiaro, Kim Stellmack | 4:20.56 | - | |
| 5. | 11 | Illinois-Chicago | B | Aimee Schuh, Jennifer Johnson, Carla Wilson, Maggie Banasik | 4:24.38 | - | |
| 6. | 12 | Concordia (Ill.) | A | Joshlynn Eaton, Allison Sapiro, Savanna Ashbaugh, Danyale Worsham | 4:27.32 | - | |
| 7. | 13 | Olivet Nazarene | C | Kortney Ellingboe, Desiree O'Brien, Lindsay Lester, Jillian Versweyveld | 4:35.15 | - | |
| 8. | 15 | Olivet Nazarene | D | Janina Roche, Leah Livingston, Janalis Roche, Samantha Clark | 4:37.85 | - |
| Heat Pl. | Overall | Team | Squad | Athletes | Time | Score |
| 1. | 1 | Illinois-Chicago | A | Jaime Johnson, Tess Ehrhardt, Ariel Kirby, Rebecca Zaiter | 3:55.06 | 10 | |
| 2. | 2 | Olivet Nazarene | A | Alexandra Ortiz, Kamaria Goedhart, Natalie Puent, Rachel Carman | 3:57.25 | 8 | |
| 3. | 3 | Clarke | A | Megan Lehmkuhl, Samantha Francois, Jasmine Reisberg, Hannah Day | 3:59.78 | 6 | |
| 4. | 4 | Judson | A | Kristal Pitts, Kim Peek, Tess Tyton, Marilyn McDougall | 4:12.76 | 5 | |
| 5. | 7 | Valparaiso | A | Kelli Wosick, Malea Buck, Patty Stellfox, Grace Shemwell | 4:17.07 | 2 | |
| 6. | 9 | Concordia (Wis.) | A | Kristin Sitte, Caitlyn Stern, Lauren Frisque, Jessica Hennig | 4:19.62 | - |