| 1
| Bowers , Jahniya | SO-2 | Youngstown St. | 24.24 | Nittany Lion Challenge | Jan 15, 2022 |
| 2
| Henderson, Suerethia | JR-3 | Youngstown St. | 24.84 | YSU Collegiate Holiday Classic | Dec 10, 2021 |
| 3
| Bradley, Azsah | | Oakland | 24.85 | SVSU Holiday Open and Multis | Dec 3, 2021 |
| 4
| Shipley, Lynsey | SR-4 | Northern Kentucky | 24.91# | 2021 Mastodon Opener | Dec 4, 2021 |
| 5
| Block, Natalie | SO-2 | Milwaukee | 24.93 | Hawkeye Invite | Jan 14, 2022 |
| 6
| Matlock , Kyndia | SO-2 | Youngstown St. | 25.05 | YSU Indoor Track & Field Icebreaker | Dec 3, 2021 |
| 7
| Worthy, Makiya | FR-1 | Oakland | 25.09 | SVSU Holiday Open and Multis | Dec 3, 2021 |
| 8
| Phillips, Emily | SR-4 | Northern Kentucky | 25.23 | 2022 Jim Green Track & Field Invitational | Jan 14, 2022 |
| 9
| Walker, Briana | | Oakland | 25.26 | SVSU Holiday Open and Multis | Dec 3, 2021 |
| 10 | Murry, Madison | FR-1 | Youngstown St. | 25.35 | Nittany Lion Challenge | Jan 15, 2022 |
| 11 | Sabourin, Payton | | Oakland | 25.37 | SVSU Holiday Open and Multis | Dec 3, 2021 |
| 12 | Dumas, Olivia | FR-1 | Illinois-Chicago | 25.39 | Blue Demon Holiday Invite | Dec 10, 2021 |
| 13 | Thomas, Dominique | FR-1 | Milwaukee | 25.47 | Hawkeye Invite | Jan 14, 2022 |
| 14 | Kinsey, Teddi | FR-1 | Youngstown St. | 25.77 | YSU Indoor Track & Field Icebreaker | Dec 3, 2021 |
| 15 | Knowles, Mone | JR-3 | Detroit Mercy | 25.83 | 2021 Blue & Gold Invitational | Dec 3, 2021 |
| 16 | Franczkowski, Logan | FR-1 | Youngstown St. | 25.84 | YSU Collegiate Holiday Classic | Dec 10, 2021 |
| 17 | Vann-Scott, Marthea | | Oakland | 25.95 | SVSU Holiday Open and Multis | Dec 3, 2021 |
| 18 | LaMons, Shaneese | | Oakland | 25.99 | SVSU Holiday Open and Multis | Dec 3, 2021 |
| 19 | Yanders, Jordan | FR-1 | Purdue Fort Wayne | 26.03 | Indiana Tech: Strive for Greatness Indoor | Dec 10, 2021 |
| 19 | Miles, Amani | SR-4 | IUPUI | 26.03# | 2021 Mastodon Opener | Dec 4, 2021 |
| 21 | McDanel, Hannah | FR-1 | Robert Morris | 26.04 | YSU Indoor Track & Field Icebreaker | Dec 3, 2021 |
| 22 | Ervin, Dynesty | SO-2 | Cleveland St. | 26.12 | Marshall Women's Classic | Jan 15, 2022 |
| 23 | Moran, Bailey | SO-2 | Illinois-Chicago | 26.13 | Windy City Classic | Dec 3, 2021 |
| 23 | Clark, Katie | JR-3 | Purdue Fort Wayne | 26.13# | 2021 Mastodon Opener | Dec 4, 2021 |
| 25 | Armstrong, Andrea | JR-3 | Northern Kentucky | 26.16 | 2022 Jim Green Track & Field Invitational | Jan 14, 2022 |
| 26 | Hudson-Turpin, Jesseca | SO-2 | Purdue Fort Wayne | 26.19# | 2021 Mastodon Opener | Dec 4, 2021 |
| 27 | Benton, Brenea | | Oakland | 26.24 | SVSU Holiday Open and Multis | Dec 3, 2021 |
| 28 | Athan, Anya | SR-4 | Milwaukee | 26.28 | Hawkeye Invite | Jan 14, 2022 |
| 29 | Laundrie, Vanessa | SO-2 | Milwaukee | 26.29 | Hawkeye Invite | Jan 14, 2022 |
| 29 | Raymond, Maddie | FR-1 | Robert Morris | 26.29 | YSU Indoor Track & Field Icebreaker | Dec 3, 2021 |
| 31 | Cunningham , Cyncere | FR-1 | Youngstown St. | 26.44 | Akron-Indoor-Quad | Jan 14, 2022 |
| 32 | Brandon, Angel | | Oakland | 26.55 | SVSU Holiday Open and Multis | Dec 3, 2021 |
| 33 | Reed, Jai | SO-2 | Purdue Fort Wayne | 26.56 | SVSU Classic | Jan 14, 2022 |
| 34 | Moore, Elicia | JR-3 | Robert Morris | 26.63 | Nittany Lion Challenge | Jan 15, 2022 |
| 35 | Pandazis, Haley | JR-3 | Purdue Fort Wayne | 26.77# | 2021 Mastodon Opener | Dec 4, 2021 |
| 36 | Kowalzcuk, Natalie | FR-1 | Illinois-Chicago | 27.05 | Windy City Classic | Dec 3, 2021 |
| 36 | Oberhaus, Mariah | FR-1 | Purdue Fort Wayne | 27.05# | 2021 Mastodon Opener | Dec 4, 2021 |
| 38 | Hoppe, Courtney | JR-3 | Milwaukee | 27.06 | Hawkeye Invite | Jan 14, 2022 |
| 38 | Wikfeldt, Josefin | FR-1 | Purdue Fort Wayne | 27.06# | 2021 Mastodon Opener | Dec 4, 2021 |
| 40 | Hallman, Naomi | SO-2 | Oakland | 27.07 | SVSU Classic | Jan 14, 2022 |
| 41 | Terry, Marie | JR-3 | IUPUI | 27.09# | 2021 Mastodon Opener | Dec 4, 2021 |
| 42 | Kruiswijk, Louiza | FR-1 | Purdue Fort Wayne | 27.25 | SVSU Classic | Jan 14, 2022 |
| 43 | Rutlege, Shaina | SO-2 | Northern Kentucky | 27.26# | 2021 Mastodon Opener | Dec 4, 2021 |
| 44 | Klatkiewicz, Brooke | FR-1 | Illinois-Chicago | 27.33 | Windy City Classic | Dec 3, 2021 |
| 45 | Rogers, Kaitlynn | JR-3 | Illinois-Chicago | 27.35 | Windy City Classic | Dec 3, 2021 |
| 46 | Volk, Kortnie | SO-2 | Milwaukee | 27.41 | Hawkeye Invite | Jan 14, 2022 |
| 47 | Oldfin, Brooke | SR-4 | Robert Morris | 27.56 | YSU Indoor Track & Field Icebreaker | Dec 3, 2021 |
| 48 | McHenry, Payton | JR-3 | Purdue Fort Wayne | 27.70 | Indiana Tech: Strive for Greatness Indoor | Dec 10, 2021 |
| 49 | Graham, Alexis | FR-1 | Oakland | 27.72 | SVSU Classic | Jan 14, 2022 |
| 50 | Uebersetzig, Ashlyn | FR-1 | Milwaukee | 27.79 | Hawkeye Invite | Jan 14, 2022 |
| 51 | Crosby, Brooke | FR-1 | Milwaukee | 27.93 | Hawkeye Invite | Jan 14, 2022 |
| 51 | Dahl, Haley | SO-2 | Illinois-Chicago | 27.93 | Windy City Classic | Dec 3, 2021 |
| 53 | Parker, Gabriella | SO-2 | Robert Morris | 27.94 | Nittany Lion Challenge | Jan 15, 2022 |
| 54 | Johnson, Selena | SO-2 | Purdue Fort Wayne | 28.06 | SVSU Classic | Jan 14, 2022 |
| 55 | Moore, Katie | FR-1 | IUPUI | 28.09# | Gene Edmonds Invitational | Jan 8, 2022 |
| 56 | Krauth, Alexa | SO-2 | Detroit Mercy | 28.12 | 2021 Blue & Gold Invitational | Dec 3, 2021 |
| 57 | Pankow, Alli | JR-3 | Cleveland St. | 28.15 | YSU Indoor Track & Field Icebreaker | Dec 3, 2021 |
| 58 | George, Errisa | FR-1 | Robert Morris | 28.94 | YSU Indoor Track & Field Icebreaker | Dec 3, 2021 |
| 59 | Naughton, Bethany | FR-1 | Robert Morris | 29.09 | YSU Indoor Track & Field Icebreaker | Dec 3, 2021 |
| 60 | Carr, Emma | SO-2 | Wright State | 29.51 | Wittenberg Opener | Dec 4, 2021 |
| 61 | Ruhlen, Alycea | JR-3 | Wright State | 30.45 | Marshall Women's Classic | Jan 15, 2022 |
| 62 | Ball, Kira | FR-1 | Wright State | 30.94 | Wittenberg Opener | Dec 4, 2021 |
| 63 | Conway, Colette | FR-1 | Cleveland St. | 31.01 | Marshall Women's Classic | Jan 15, 2022 |
